Author/Authors :
Latifa Bouissane، نويسنده , , Said El Kazzouli، نويسنده , , Jean-Michel Leger، نويسنده , , Christian Jarry، نويسنده , , El Mostapha Rakib، نويسنده , , Mostafa Khouili، نويسنده , , Gérald Guillaumet، نويسنده ,
Abstract :
In this paper, the synthesis of bi- and trisubstituted indazoles was described. 4-Alkoxy-7-aminoprotected-indazole or 7-aminoprotected-indazole derivatives were prepared selectively using SnCl2 in alcohol or SnCl2 in ethyl acetate, respectively. The effects of the halogen atom in position 3 and of the N-alkylation in N-1 position of 7-nitroindazoles were investigated.
Keywords :
Alcohols , cross-coupling reaction , Nucleophilic addition , indazoles
