Title of article
Reductive metalation of 1,2-diaryl-substituted ethenes: synthetic applications
Author/Authors
Ugo Azzena، نويسنده , , Domenica Giovanna Dettori، نويسنده , , Caterina Lubinu، نويسنده , , Alberto Mannu، نويسنده , , Luisa Pisano، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
6
From page
8663
To page
8668
Abstract
Reduction of 1,2-diaryl-substituted ethenes with Na metal in dry THF allowed easy access to a variety of 1,2-diaryl-1,2-disodiumethanes. These diorganometallic intermediates were elaborated into the corresponding 1,2-diarylethanes (aqueous work up), or cycloalkylated with 1,3-dichloropropanes. The last reaction led to a highly diastereoselective synthesis of trans-1,2-diaryl-substituted cyclopentanes.
Keywords
Dicarbanions , Reduction , Cycloalkylation , metalation , Stilbenes
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1089091
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