Author/Authors :
Laila Kamoune، نويسنده , , Wim M. De Borggraeve، نويسنده , , Bie M.P. Verbist، نويسنده , , Jozef Vanden Broeck، نويسنده , , Geoffrey M. Coast، نويسنده , , Frans Compernolle ، نويسنده , , Georges Hoornaert، نويسنده ,
Abstract :
Based on a receptor interaction model, simplified analogues of insect kinins were prepared. The compounds were templated on a conformationally restricted amino piperidinone carboxylate scaffold. The conformation of the analogues was studied by NMR and the biological activity of the compounds was tested in a bio-assay.
