Title of article :
Synthesis of the phthalide-containing anti-Helicobacter pylori agents CJ-13,015, CJ-13,102, CJ-13,103, CJ-13,104 and CJ-13,108
Author/Authors :
Margaret A. Brimble، نويسنده , , Christopher L. Flowers، نويسنده , , James K. Hutchinson، نويسنده , , James E. Robinson، نويسنده , , Matthew Sidford، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
Flexible racemic syntheses of the phthalide-containing antibiotics CJ-13,015, CJ-13,102, CJ-13,103, CJ-13,104 and CJ-13,108 that inhibit Helicobacter pylori have been carried out in a convergent fashion by Wittig coupling of a phthalide-containing aldehyde fragment with an appropriate phosphorous ylide.
Keywords :
Wittig reaction , Helicobacter pylori , phthalides
Journal title :
Tetrahedron
Journal title :
Tetrahedron
