Title of article
A convergent and stereoselective synthesis of a seco-precursor of macrolactin A
Author/Authors
Shukun Li، نويسنده , , Xiangshu Xiao، نويسنده , , Xuebin Yan، نويسنده , , Xuejun Liu، نويسنده , , Rui Xu، نويسنده , , Donglu Bai، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
8
From page
11291
To page
11298
Abstract
A seco-precursor of macrolactin A was synthesized by coupling two advanced segments. Wittig reaction and Horner–Emmons reaction were utilized to construct the three characteristic E,Z and E,E dienes. The C1–C10 segment was synthesized through Horner–Emmons reaction with phosphonate reagent. The α-alkylation of sulfone stabilized anion with allyl bromide followed by desulfonation gave the C11–C24 segment.
Keywords
Horner–Emmons reaction , macrolactin A , seco-Precursor
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1089355
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