Title of article :
Total synthesis of lamellarins D, L, and N
Author/Authors :
Naotaka Fujikawa، نويسنده , , Takeshi Ohta، نويسنده , , Tomohiro Yamaguchi، نويسنده , , Tsutomu Fukuda، نويسنده , , Fumito Ishibashi، نويسنده , , Masatomo Iwao، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
Total synthesis of cytotoxic marine alkaloids, lamellarins D, L, and N, has been achieved by using Hinsberg-type pyrrole synthesis and palladium-catalyzed Suzuki–Miyaura coupling of the 3,4-dihydroxypyrrole bistriflate as the key reactions. The total yields of lamellarins D, L, and N from the common intermediate are 54, 58, and 50%, respectively.
Keywords :
Total synthesis , Lamellarin , Hinsberg reaction , Suzuki–Miyaura coupling
Journal title :
Tetrahedron
Journal title :
Tetrahedron
