Efficient synthesis of 18–40 membered macrocyclic polyoxadiamides and polyoxatetraamides via ring closing metathesis

Ring closing metathesis of the appropriate 1,ω-dienes led to efficient synthetic approaches towards the corresponding macrocyclic polyoxadiamides and tetraamides with 18–40 membered ring sizes in good to excellent yields using Grubbsʹ catalyst.