Title of article
New strategy towards the efficient solid phase synthesis of cyclopeptides
Author/Authors
Thomas Berthelot، نويسنده , , Mario Gonçalves، نويسنده , , Georges Laïn، نويسنده , , Karine Estieu-Gionnet، نويسنده , , Gérard Déléris، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
7
From page
1124
To page
1130
Abstract
Synthetic cyclopeptides, and particularly those designed from VEGF structure, present considerable interest for the development of nanodevices devoted to tumor imaging or drug delivery. In order to obtain functionalizable cyclopeptides, we herein present a novel efficient way based on Fmoc-Lys-ODmab use, which was applied to the synthesis of c(PHGRIK) cyclopeptide.
Keywords
cyclopeptides , Nanodevice , On-resin cyclization , Dmab ester , Lysine
Journal title
Tetrahedron
Serial Year
2006
Journal title
Tetrahedron
Record number
1089580
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