Title of article
Practical and efficient entry to isoflavones by Pd(0)/C-mediated Suzuki–Miyaura reaction. Total synthesis of geranylated isoflavones
Author/Authors
François-Xavier Felpin، نويسنده , , Cécile Lory، نويسنده , , Hawaa Sow، نويسنده , , Samir Acherar، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
7
From page
3010
To page
3016
Abstract
A scalable synthesis of isoflavones taking advantage of the Suzuki–Miyaura reaction catalyzed by Pd(0)/C is described. The approach developed has been extended to the total synthesis of 7-O-geranylformononetin, griffonianone D, and conrauinone D, which did not display cytotoxicity against human HeLa carcinoma cells. In addition, this study established unambiguously the absolute configuration of natural griffonianone D.
Keywords
Pd/C , Suzuki–Miyaura reaction , Isoflavones , 7-O-Geranylformononetin , Conrauinone D , Griffonianone D
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1090518
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