Title of article
Different N–C–N formation reactions of aromatic aldehydes and thiohydantoins controlled by Lewis acid promoters
Author/Authors
Feifei Gao، نويسنده , , Guangliang Zhang، نويسنده , , Suoqin Zhang، نويسنده , , Yueming Cheng، نويسنده , , Zhan Shi، نويسنده , , Yaoxian Li، نويسنده , , Junlong Gao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
9
From page
3973
To page
3981
Abstract
A three-component reaction of aromatic aldehydes, acetonitrile, and 2-thiohydantoins promoted by TiCl4 was discovered, and a different N–C–N bond-forming reaction took place with FeCl3, AlCl3 or BF3·Et2O as promoter. The thiohydantoin derivatives 1 and 3 were synthesized in moderate to high yields. A plausible mechanism for the formation of 1 and 3 is suggested.
Keywords
2-Thiohydantoins , Lewis acids , Multicomponent reactions
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1090690
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