Title of article
Synthesis of migrastatin and its macrolide core
Author/Authors
Sébastien Reymond، نويسنده , , Janine Cossy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
12
From page
5918
To page
5929
Abstract
Migrastatin and its macrolactone subunit are potent antimetastatic agents. Both were synthesized by using a ring-closing metathesis (RCM) to establish the macrolactone core, and the control of the (Z)-trisubstituted double bond at C11–C12 was achieved by using a Still–Gennari olefination.
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1091047
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