• Title of article

    Synthesis of migrastatin and its macrolide core

  • Author/Authors

    Sébastien Reymond، نويسنده , , Janine Cossy، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2007
  • Pages
    12
  • From page
    5918
  • To page
    5929
  • Abstract
    Migrastatin and its macrolactone subunit are potent antimetastatic agents. Both were synthesized by using a ring-closing metathesis (RCM) to establish the macrolactone core, and the control of the (Z)-trisubstituted double bond at C11–C12 was achieved by using a Still–Gennari olefination.
  • Journal title
    Tetrahedron
  • Serial Year
    2007
  • Journal title
    Tetrahedron
  • Record number

    1091047