Author/Authors :
Alexandra M.M. Antunes، نويسنده , , Vasco D.B. Bonif?cio، نويسنده , , Susana C.C. Nascimento، نويسنده , , Ana M. Lobo، نويسنده , , Paula S. Branco، نويسنده , , Sundaresan Prabhakar، نويسنده ,
Abstract :
The palladium(II)-promoted reaction of a variety of olefins and bromamine-T provided N-tosyl-2-substituted aziridines under mild conditions. Olefins bearing chiral appendages gave only a poor to modest diastereoselectivity. Appropriate deuterated olefins were selected to study the stereochemistry of the reaction. A Pd(IV) intermediate is proposed as the aziridinating species.
Keywords :
Bromamine-T , aziridination , Palladium(II) , Catalysis
