• Title of article

    Synthesis of (−)-neplanocin A with the highest overall yield via an efficient Mitsunobu coupling

  • Author/Authors

    Benoît Y. Michel، نويسنده , , Peter Strazewski، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2007
  • Pages
    6
  • From page
    9836
  • To page
    9841
  • Abstract
    Neplanocin A was synthesized in very high isolated yield and purity, in 10 steps from d-ribose via an efficient Mitsunobu coupling using N6-bis-Boc-protected adenine. In fact, this synthesis is a short pathway to enantiopure neplanocin A giving the highest published overall yield.
  • Keywords
    Antiviral , Antitumor , carbocyclic nucleosides , Mitsunobu coupling , Fürstnerיs catalyst , Metathesis
  • Journal title
    Tetrahedron
  • Serial Year
    2007
  • Journal title
    Tetrahedron
  • Record number

    1093244