Title of article
Synthesis of (−)-neplanocin A with the highest overall yield via an efficient Mitsunobu coupling
Author/Authors
Benoît Y. Michel، نويسنده , , Peter Strazewski، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
6
From page
9836
To page
9841
Abstract
Neplanocin A was synthesized in very high isolated yield and purity, in 10 steps from d-ribose via an efficient Mitsunobu coupling using N6-bis-Boc-protected adenine. In fact, this synthesis is a short pathway to enantiopure neplanocin A giving the highest published overall yield.
Keywords
Antiviral , Antitumor , carbocyclic nucleosides , Mitsunobu coupling , Fürstnerיs catalyst , Metathesis
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1093244
Link To Document