Enantioselective ethylation of aldehydes using a regenerable polymer-supported N-picolylvalinol tridentate ligand

A supported pyridine-based tridentate chiral ligand has been prepared and evaluated for enantioselective addition of diethylzinc to aldehydes. The catalyst allowed the preparation of various chiral alcohols with the R configuration in good yields and enantiomeric excesses (up to 93%) and was found reusable.