Title of article
Batzelladine alkaloids from the caribbean sponge Monanchora unguifera and the significant activities against HIV-1 and AIDS opportunistic infectious pathogens
Author/Authors
Hui-Ming Hua، نويسنده , , Jiangnan Peng، نويسنده , , D. Chuck Dunbar، نويسنده , , Raymond F. Schinazi، نويسنده , , Arcadio G. de Castro Andrews، نويسنده , , Carmen Cuevas، نويسنده , , Luis F. Garcia-Fernandez، نويسنده , , Michelle Kelly، نويسنده , , Mark T. Hamann، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
10
From page
11179
To page
11188
Abstract
Five new polycyclic guanidine alkaloids, 16β-hydroxycrambescidin 359 (1), batzelladines K, L, M, and N (2–5), along with the previously reported ptilomycalin A (6), crambescidine 800 (7), batzelladine C (8), and dehydrobatzelladine C (9), were isolated from the Jamaican sponge Monanchora unguifera. Their structures were assigned on the basis of detailed analysis of 1D and 2D NMR, and mass spectral data. Their activities against cancer cell lines, protozoa, HIV-1 and AIDS opportunistic infectious pathogens (AIDS-OIs) including Mtb were evaluated.
Journal title
Tetrahedron
Serial Year
2007
Journal title
Tetrahedron
Record number
1093394
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