Author/Authors :
Taichi Kusakabe، نويسنده , , Keisuke Kato، نويسنده , , Satoshi Takaishi، نويسنده , , Shigeo Yamamura، نويسنده , , Tomoyuki Mochida، نويسنده , , Hiroyuki Akita، نويسنده , , Tatʹyana A. Peganova، نويسنده , , Nikolai V. Vologdin، نويسنده , , Oleg V. Gusev، نويسنده ,
Abstract :
Oxidative cyclization–carbonylation of 2-alkyl-2-propargylcyclohexane-1,3-diones mediated by Pd(TFA)2/2,2′-isopropylidenebis[(4R)-4-(3,4-dimethoxyphenyl)-2-oxazoline] 28 afforded bicyclic-β-alkoxyacrylates in 51–74% yields with 72–82% ee. The products containing quaternary carbon were converted to optically active hydrindanes 33.
Keywords :
Asymmetric , Bisoxazoline , Wacker-type cyclization , Hydrindane , Carbonylation , Palladium
