Author/Authors :
Stefania Fioravanti، نويسنده , , Davide Massari، نويسنده , , Alberto Morreale، نويسنده , , Lucio Pellacani، نويسنده , , Paolo A. Tardella، نويسنده ,
Abstract :
Starting from a library of 2-l-α-amino acyl (E)-acrylonitriles, different short 2-cyano and 2-amido aziridinyl peptides, potential protease inhibitors, were obtained under parallel solution-phase conditions. The transformations include careful selection of conditions for aziridine deprotection and cyano group partial hydrolysis.
