Title of article
Organocatalysed three-component domino synthesis of 1,4-dihydropyridines under solvent free conditions
Author/Authors
Atul Kumar، نويسنده , , Ram Awatar Maurya، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
6
From page
3477
To page
3482
Abstract
An organocatalysed protocol for one-pot synthesis of 1,4-dihydropyridines via three-component coupling of cinnamaldehyde, aniline and β-keto esters under solvent free conditions at ambient temperature is reported. The reaction is generally very fast and the products are obtained in high yield. The catalytic activity of small organic molecules like amino acids (acidic, basic and neutral), ephedrine and cinchona alkaloids was studied.
Keywords
Domino synthesis , solvent free , Organocatalyst , Multi-component , 4-Dihydropyridines , 1
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1093950
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