Title of article :
From cyclopentadiene to isoxazoline-carbocyclic nucleosides: a rapid access to biological molecules through aza-Diels–Alder reactions
Author/Authors :
Paolo Quadrelli، نويسنده , , Andrea Piccanello، نويسنده , , Mariella Mella، نويسنده , , Antonino Corsaro، نويسنده , , Venerando Pistarà، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Pages :
7
From page :
3541
To page :
3547
Abstract :
A rapid access to carbocyclic nucleosides containing a fused isoxazoline ring is proposed through the Grieco cycloaddition of cyclopentadiene to iminium salts. The prolific elaboration of the isoxazoline cycloadducts allowed preparation of the target aminols through the unmasking of the hydroxymethylene group at the C3 level of the azanorbornene structure. The heterocyclic aminols are readily converted into nucleosides via the linear construction of purine heterocycles.
Journal title :
Tetrahedron
Serial Year :
2008
Journal title :
Tetrahedron
Record number :
1093958
Link To Document :
بازگشت