Title of article
Reaction of benzoyl chlorides with Huisgenʹs zwitterion: synthesis of functionalized 2,5-dihydro-1H-pyrroles and tetrasubstituted furans
Author/Authors
Issa Yavari، نويسنده , , Ako Mokhtarporyani-Sanandaj، نويسنده , , Loghman Moradi، نويسنده , , Anvar Mirzaei، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
5
From page
5221
To page
5225
Abstract
The 1:1 intermediate generated by the addition of alkyl(aryl) isocyanides to dimethyl acetylenedicarboxylate is trapped by benzoyl chloride to yield functionalized 2,5-dihydro-1H-pyrroles. The presence of electron-withdrawing groups at the para position of benzoyl chloride leads to tetrasubstituted furans. The structures of these products were confirmed by single-crystal X-ray diffraction studies.
Keywords
Electron-deficient acetylenes , 2 , isocyanides , 5-Dihydro-1H-pyrrole , Benzoyl chloride , Aminofurans
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094131
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