Title of article
A formal total synthesis of the marine alkaloid aaptamine
Author/Authors
Enrique L. Larghi، نويسنده , , Blaise V. Obrist، نويسنده , , Teodoro S. Kaufman، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
10
From page
5236
To page
5245
Abstract
A new strategy for the synthesis of benzo[de][1,6]naphthyridine derivative 2,3,3a,4,5,6-hexahydroaaptamine, which involves the construction of the isoquinoline ring after elaboration of the quinoline moiety, is described. Since 2,3,3a,4,5,6-hexahydroaaptamine has been previously synthesized as a key intermediate en route to the marine alkaloid aaptamine, access to this compound represents a formal total synthesis of the natural product.
Keywords
5 , 6-Hexahydroaaptamine , Formal total synthesis , aaptamine , 6]naphthyridine alkaloids , 2 , 3 , 4 , 3a
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094133
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