Title of article
Synthesis of 2′-C-methyl-branched isonucleosides
Author/Authors
Tony Bouisset، نويسنده , , Gilles Gosselin، نويسنده , , Ludovic Griffe، نويسنده , , Jean-Christophe Meillon، نويسنده , , Richard Storer، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
5
From page
6657
To page
6661
Abstract
Novel regioisomers of 2′-methyl-branched nucleosides were designed and synthesized to mimic potent anti-viral drugs like Valopicitabine. The short and efficient synthesis of the targets involves a one-pot tosylation/cyclization step that leads to an activated furan scaffold on which the isonucleosides were built.
Keywords
Nucleoside analogues , Valopicitabine , Hepatitis C , Isonucleosides , Anti-virals
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094301
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