Title of article
Jaspamides H–L, new actin-targeting depsipeptides from the sponge Jaspis splendans
Author/Authors
Fulvio Gala، نويسنده , , Maria Valeria DʹAuria، نويسنده , , Simona De Marino، نويسنده , , Valentina Sepe، نويسنده , , Franco Zollo، نويسنده , , Charles D. Smith، نويسنده , , Jean E. Copper، نويسنده , , Angela Zampella، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
7127
To page
7130
Abstract
Continued investigation of cytotoxic extracts of the marine sponge Jaspis splendans has resulted in the discovery of jaspamides H–L (2–5). Their structures were determined by interpretation of their NMR and ESIMS data. All compounds exhibited potent cytotoxic activities and were shown to cause microfilament disruption. Biological activity and structural elucidation are reported here.
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094351
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