Click chemistry as an efficient tool to access β-cyclodextrin dimers

The Cu(I)-catalyzed azide–alkyne cycloaddition has enabled practical and efficient preparation of hydroxylated, permethylated and peracylated β-cyclodextrin dimers in good yields starting from mono-6-azido-β-cyclodextrin and ortho-, meta- or para-bis-(prop-2-ynyloxy)benzenes as spacers.