Title of article
A rapid and facile synthesis of new spiropyrimidines from 5-(2-arylethylidene-2-oxo)-1,3-dimethylpyrimidine-2,4,6-triones
Author/Authors
Lali L. Gozalishvili، نويسنده , , Tetyana V. Beryozkina، نويسنده , , Irina V. Omelchenko، نويسنده , , Roman I. Zubatyuk، نويسنده , , Oleg V. Shishkin، نويسنده , , Nadezhda N. Kolos، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
7
From page
8759
To page
8765
Abstract
A series of new tetraazaspiro[5,5]-undec-4-ene-2,7,9,11-tetraones have been obtained by reaction of 5-(2-arylethylidene-2-oxo)-1,3-dimethylpyrimidine-2,4,6-triones with ureas. A three-component one-pot procedure to the spiranes synthesis was also developed. One-pot reaction of arylglyoxals, 1,3-dimethylbarbituric acid, and dimethylurea led to imidazolyl-1,3-dimethylbarbituric acids. Mechanisms of studied reactions were discussed.
Keywords
Knoevenagel reaction , Spiropyrimidines , One-pot synthesis , ? , ?-Unsaturated ketones , Arylglyoxals , Ureas
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094553
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