• Title of article

    Felkin–Anh selectivity in Rh(bisoxazolinylphenyl)-catalyzed reductive aldol coupling reaction: asymmetric synthesis of stereotriads

  • Author/Authors

    Toru Hashimoto، نويسنده , , Junichi Ito، نويسنده , , Hisao Nishiyama، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    5
  • From page
    9408
  • To page
    9412
  • Abstract
    The catalytic reductive aldol coupling of 2-phenylpropionaldehyde and acrylate derivatives with rhodium-bisoxazolinyl catalysts resulted in high Felkin–Anh selectivity (β,γ-syn) up to 98% accompanied by α,β-anti diastereoselectivity and high enantiomeric excesses up to 99%.
  • Keywords
    Rhodium , Felkin–Anh , Bisoxazoline , Asymmetric catalysis , Reductive aldol reaction
  • Journal title
    Tetrahedron
  • Serial Year
    2008
  • Journal title
    Tetrahedron
  • Record number

    1094624