Title of article
Effective synthetic routes to activated pyrrolo[3,2,1-hi]indoles
Author/Authors
Jumina، نويسنده , , Paul A. Keller، نويسنده , , Naresh Kumar، نويسنده , , David StC. Black، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
8
From page
11603
To page
11610
Abstract
Pyrrolo[3,2,1-hi]indoles have been formed by the aldol cyclisation of 7-formyl-N-indolylacetates. The synthetic sequence incorporates three steps from suitably activated indoles: these are alkylation at nitrogen with a bromoacetic ester, formylation at C7 and an aldol condensation between these two substituents. An X-ray crystal structure of pyrrolo[3,2,1-hi]indole 24 is described.
Keywords
Pyrroloindoles , Aldol reaction , Indoles , Cyclisation reactions
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094889
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