Title of article
Direct-type vinylogous Mukaiyama–Michael addition reactions involving pyrrolinone donors
Author/Authors
Andrea Sartori، نويسنده , , Claudio Curti، نويسنده , , Lucia Battistini، نويسنده , , Paola Burreddu، نويسنده , , Gloria Rassu، نويسنده , , Giorgio Pelosi، نويسنده , , Giovanni Casiraghi، نويسنده , , Franca Zanardi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
9
From page
11697
To page
11705
Abstract
The direct Mukaiyama–Michael addition of vinylogous tetramate donors to a number of different Michael acceptors has been easily executed, by employing the TMSOTf/Et3N mixture as soft Lewis acid/base promoter agent. Richly functionalized, highly manipulable γ-substituted pyrrolinone products were practically synthesized in acceptable to excellent yields, and with diastereoselectivities heavily relying upon the substituent at the nitrogen atom of the pyrrolinone donor.
Keywords
1 , 4-Addition reaction , Pyrrolin-2-ones , 4-Methoxytetramates , Vinylogous Michael reaction
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094901
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