Title of article
A convenient route to chiral γ-lactones via asymmetric hydrogenation of γ-ketoesters using the RuCl3–BINAP–HCl catalytic system
Author/Authors
Eugenia V. Starodubtseva، نويسنده , , Olga V. Turova، نويسنده , , Maxim G. Vinogradov، نويسنده , , Lilia S. Gorshkova، نويسنده , , Vladimir A. Ferapontov، نويسنده , , Marina I. Struchkova، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
5
From page
11713
To page
11717
Abstract
A convenient one-step synthesis of chiral γ-lactones has been performed. The method is based on enantioselective hydrogenation of γ-ketoesters using the RuCl3–BINAP–HCl catalytic system. Chiral γ-lactones (91–99% ee) have been isolated in 57–88% yield.
Keywords
asymmetric hydrogenation , Chiral ?-lactones
Journal title
Tetrahedron
Serial Year
2008
Journal title
Tetrahedron
Record number
1094903
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