Title of article
Novel synthesis of fused indoles and 2-substituted indoles by the palladium-catalyzed cyclization of N-cycloalkenyl-o-haloanilines
Author/Authors
Masafumi Ueda، نويسنده , , Hideto Miyabe، نويسنده , , Okiko Miyata، نويسنده , , Takeaki Naito، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
9
From page
1327
To page
1335
Abstract
A new palladium-catalyzed cyclization of N-alkenyl-o-haloanilines with selective isomerization of a double bond followed by formal 5-endo-trig cyclization was developed. A variety of fused and 2-substituted indoles were synthesized from enaminoesters prepared by condensation of β-ketoesters and o-iodoaniline.
Keywords
Palladium , Heck reaction , Olefin isomerization , Enamine , Indole
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1095093
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