Title of article
Efficient synthesis of pyrano[2,3-c]coumarins via intramolecular domino Knoevenagel hetero-Diels–Alder reactions
Author/Authors
Malihe Javan Khoshkholgh، نويسنده , , Minoo Lotfi، نويسنده , , Saeed Balalaie، نويسنده , , Frank Rominger، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
7
From page
4228
To page
4234
Abstract
The domino Knoevenagel hetero-Diels–Alder reaction of the O-propargylated salicylaldehydes and 4-hydroxycoumarin leads to pyrano[2,3-c]coumarins 3 and pyrano[2,3-c]chromones 4 in high yield in the presence of CuI as a Lewis acid. In all cases, the reaction was shown to exhibit high regioselectivity and form product 3 as main product.
Keywords
Copper catalysis , alkynes , domino reactions , oxygen heterocycles , Cycloadditions
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1095441
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