Title of article
Synthesis of chiral oxime ethers based on regio- and enantioselective allylic substitution catalyzed by iridium–pybox complex
Author/Authors
Hideto Miyabe، نويسنده , , Akira Matsumura، نويسنده , , Kazumasa Yoshida، نويسنده , , Yoshiji Takemoto، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
7
From page
4464
To page
4470
Abstract
The oxygen atom of oximes acts as a reactive nucleophile in the iridium-catalyzed allylic substitution of unsymmetrical substrates to give the branched oxime ethers. Among several chiral ligands evaluated, the iridium complex of pybox ligand having phenyl group catalyzed the allylic substitution of phosphates with high activity to form the branched oxime ethers with good enantioselectivities.
Keywords
Enantioselectivity , oxime ether , Allylic substitution , Iridium , Oxime
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1095469
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