Title of article :
A rhodium(I)-xylyl-BINAP catalyzed asymmetric ynamide-[2+2+2] cycloaddition in the synthesis of optically enriched N,O-biaryls
Author/Authors :
Jossian Oppenheimer، نويسنده , , Whitney L. Johnson، نويسنده , , Ruth Figueroa، نويسنده , , Ryuji Hayashi، نويسنده , , Richard P. Hsung، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
A rhodium(I)-xylyl-BINAP catalyzed asymmetric [2+2+2] cycloaddition of achiral conjugated aryl ynamides with various diynes is described here. This asymmetric cycloaddition provides a series of structurally interesting chiral N,O-biaryls with excellent enantioselectivity along with a modest diastereoselectivity with respect to both C–C and C–N axial chirality.
Keywords :
Aryl ynamides , Chiral N , O-biaryls , Rhodium(I) catalyst and (S)-xylyl-BINAP , C–N axial chirality , double asymmetric induction of non-point stereocenters
Journal title :
Tetrahedron
Journal title :
Tetrahedron
