Title of article :
Synthesis of 5-arylthiazoles. Comparative study between Suzuki cross-coupling reaction and direct arylation
Author/Authors :
Nicolas Primas، نويسنده , , Alexandre Bouillon، نويسنده , , Jean-Charles Lancelot، نويسنده , , Hussein El-Kashef، نويسنده , , Sylvain Rault، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
A facile synthetic route to the new thiazol-5-ylboronic acid pinacol ester was described herein. Its reactivity toward Suzuki cross-coupling reaction was studied to provide various 5-arylthiazoles. A comparative study between Suzuki cross-coupling reactions and palladium-catalyzed C5–H direct arylation on thiazole ring was achieved.
Keywords :
boronic ester , Suzuki cross-coupling , Direct arylation , aryl halides , Thiazole
Journal title :
Tetrahedron
Journal title :
Tetrahedron
