Title of article :
Synthesis of 2-TIPS-oxazol-5-ylboronic acid pinacol ester: efficient route to 5-(het)aryloxazoles via Suzuki cross-coupling reaction
Author/Authors :
Nicolas Primas، نويسنده , , Alexandre Bouillon، نويسنده , , Jean-Charles Lancelot، نويسنده , , Sylvain Rault، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
A facile synthetic route to the new 2-TIPS-oxazol-5-ylboronic acid pinacol ester was described herein. Its reactivity toward Suzuki cross-coupling reaction was studied to provide various 5-(het)aryloxazoles. A wide range of functions on the aryl moiety are tolerated.
Keywords :
Suzuki cross-coupling , aryl halides , boronic ester , oxazole , Silyl protecting group
Journal title :
Tetrahedron
Journal title :
Tetrahedron
