Author/Authors :
Kazuhiro Chiba، نويسنده , , Mari Sugihara، نويسنده , , Kazumi Yoshida، نويسنده , , Yuzuru Mikami، نويسنده , , Shokaku Kim، نويسنده ,
Abstract :
Hydrophobically tagged prolyl peptides were synthesized using an electrochemically modified prolyl moiety. The hydrophobic tag served a useful handle for the repetitive reaction/separation steps during solution-phase peptide synthesis. Furthermore, the tag was also effective as an anchor on solid phases for the evaluation of activity of immobilized peptides.