Title of article
An efficient three-component protocol for the synthesis of novel spiro-oxazinobarbiturates
Author/Authors
Mohammad Bagher Teimouri، نويسنده , , Tayyebeh Abbasi، نويسنده , , Saloomeh Ahmadian، نويسنده , , Mohammad Reza Poor Heravi، نويسنده , , Reihaneh Bazhrang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
5
From page
8120
To page
8124
Abstract
Some novel spiro-oxazinobarbiturate derivatives have been successfully synthesized in a one-pot, three-component cascade reaction from various azines (pyridine, isoquinoline, quinoline and phenanthridine), 1,3-dimethylalloxan, and several activated acetylenes (alkyl propiolates, dialkyl acetylenedicarboxylates, and butyne-2-one). The high bond forming efficiency (formation of new C–N, C–C, and C–O bonds) of this reaction makes it attractive for the synthesis of spiro-oxazinobarbiturates in a single operation.
Keywords
Activated acetylenes , Alloxan , azines , Multicomponent reactions , Spiro compounds
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1097764
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