Author/Authors :
Bartolo Gabriele، نويسنده , , Raffaella Mancuso، نويسنده , , Elvira Lupinacci، نويسنده , , Rosella Spina، نويسنده , , Giuseppe Salerno، نويسنده , , Lucia Veltri، نويسنده , , Angela DiBenedetto، نويسنده ,
Abstract :
A convenient and simple approach for the recyclable catalytic synthesis of substituted quinolines is presented. The method is based on CuCl2-catalyzed heterocyclization of readily available 1-(2-aminoaryl)-2-yn-1-ols in BmimBF4 as the solvent at 100 °C for 15–24 h. The solvent–catalyst system could be successfully recycled up to six times without significant loss of activity.