Title of article
Solid-phase synthesis of α-alkylserines via phase-transfer catalytic alkylation of polymer-supported 2-phenyl-2-oxazoline-4-carboxylate
Author/Authors
Jihye Lee، نويسنده , , Min-Woo Ha، نويسنده , , Taek-Soo Kim، نويسنده , , Mi-Jeong Kim، نويسنده , , Jin-Mo Ku، نويسنده , , Sang-sup Jew، نويسنده , , Hyeung-geun Park، نويسنده , , Byeong-Seon Jeong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
5
From page
8839
To page
8843
Abstract
Described is the development of a new solid-phase synthetic method for α-alkylserines in which phase-transfer catalytic alkylation of polymer-supported 2-phenyl-2-oxazoline-4-carboxylate (12) is the key step. The easy preparation of the polymer-supported substrate 12, the high chemical yield (up to 93%), and the mild cleavage conditions could make this method very practical for the synthesis of α-alkylserines.
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1097852
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