Title of article
Regioselective halogenation of aminopyrimidinyl-pyrrole carboxylic acid derivatives
Author/Authors
Ermes Vanotti، نويسنده , , Marina Caldarelli، نويسنده , , Teresa Disingrini، نويسنده , , Marcella Nesi، نويسنده , , Marco Tat?، نويسنده , , Paola Vianello، نويسنده , , Maria Menichincheri، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
6
From page
10418
To page
10423
Abstract
The regioselective synthesis of halogenated aminopyrimidinyl-pyrroles as useful scaffolds for the preparation of diversified selective kinase inhibitors is described. The chemistry is simple and mostly based on the use of N-halosuccinimides under mild reaction conditions but the regioselectivity observed is partially unexpected.
Keywords
Kinase inhibitors , Pyrimidine , Pyrrole , N-halosuccinimide , Halogenation
Journal title
Tetrahedron
Serial Year
2009
Journal title
Tetrahedron
Record number
1100333
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