Title of article
Straightforward stereoselective synthesis of polyfunctionalised cyclohexenols using a multicomponent approach
Author/Authors
Andrea Basso، نويسنده , , Luca Banfi، نويسنده , , Giuseppe Guanti، نويسنده , , Renata Riva، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
8
From page
2390
To page
2397
Abstract
An intramolecular Ugi 5-centre-4-component reaction (U-5C-4CR) followed by a palladium-catalysed ring-opening has been employed to transform oxabicycloheptene-based β-amino acids into two families of regioisomeric polyfunctionalised cyclohexenols. The whole process is completely stereoselective and enantiomerically pure products are obtained in high overall yields.
Keywords
Enantioselective synthesis , Norbornenyl amino acids , Ring-opening reactions , Multicomponent reactions , Cyclohexenols , Diversity oriented synthesis
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1100676
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