Title of article
Microwave-assisted synthesis of 4-amino-3,5-dihalopyridines
Author/Authors
Mark Pichowicz، نويسنده , , Simon Crumpler، نويسنده , , B. Edward McDonald and William L. Siegmann، نويسنده , , Julian Blagg، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
6
From page
2398
To page
2403
Abstract
4-Amino-3,5-dihalopyridines have been efficiently prepared via microwave-assisted nucleophilic aromatic substitution of 3,4,5-trihalopyridines using 1–1.1 equiv of primary and secondary amines. The reaction is also applicable to electron rich arylamines.
Keywords
Coupling , nucleophilic aromatic substitution , Pyridines , Amines , Microwave-assisted synthesis
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1100677
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