Title of article
Globular carbosilane dendrimers with mannose groups at the periphery: synthesis, characterization and toxicity in dendritic cells
Author/Authors
Paula Ortega، نويسنده , , Ma Jes?s Serram?a، نويسنده , , Ma Angeles Mu?oz-Fern?ndez، نويسنده , , F. Javier de la Mata، نويسنده , , Rafael G?mez، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
6
From page
3326
To page
3331
Abstract
A synthetic strategy has been developed for the preparation of new globular carbosilane dendrimers with mannose groups at the periphery. It consists of hydrosilylation reaction of allyl tetraacetylmannose with carbosilane dendrimers containing monohydrosilane end groups and the subsequent deacetylation reaction. Evaluation of dendrimer toxicities in dendritic cells by MTT assay were carried out, and evidence a good biocompatibility.
Keywords
Mannose , Dendritic cells , Carbosilane , Dendrimers
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1100788
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