• Title of article

    Synthesis of functionalized 3-hydroxypiperidines

  • Author/Authors

    Marloes A. Wijdeven، نويسنده , , Floris L. van Delft، نويسنده , , Floris P.J.T. Rutjes، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2010
  • Pages
    14
  • From page
    5623
  • To page
    5636
  • Abstract
    The synthetic versatility of three chemoenzymatically prepared hydroxypiperidine building blocks has been explored, resulting in a library of enantiopure functionalized piperidines. Key steps involved N-acyliminium ion-mediated CC-bond formation and cross-metathesis reactions, after which full deprotection led to the set of free 3-hydroxypiperidines.
  • Journal title
    Tetrahedron
  • Serial Year
    2010
  • Journal title
    Tetrahedron
  • Record number

    1101066