Title of article :
Highly enantioselective desymmetrizations of meso-anhydrides
Author/Authors :
Ellen Schmitt، نويسنده , , Ingo Schiffers، نويسنده , , Carsten Bolm، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
Readily available, low molecular cyclohexane-based organocatalysts promote highly enantioselective desymmetrizations of cyclic meso-anhydrides applying alcohols and benzyl mercaptan as nucleophiles. Both succinic and glutaric anhydrides furnished the corresponding products with up to 96% ee in mostly quantitative yields.
Journal title :
Tetrahedron
Journal title :
Tetrahedron
