Title of article
A synthesis of (−)-ebelactones A and B
Author/Authors
John P. Cooksey، نويسنده , , Rhonan Ford، نويسنده , , Philip J. Kocienski، نويسنده , , Béatrice Pelotier، نويسنده , , Jean-Marc Pons، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
6
From page
6462
To page
6467
Abstract
A synthesis of the β-lactone esterase inhibitors (−)-ebelactones A and B is described. The synthesis features the use of a Hoppe homoaldol reaction and a Cu(I)-mediated 1,2-metallate rearrangement of a metallated enol carbamate as key fragment linkage reactions.
Keywords
1 , Ebelactone B , Roush crotylmetallation , Ebelactone A , 2-Metallate rearrangement , Hoppe homoaldol reaction
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1101165
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