Title of article
A facile protocol for the synthesis of mono-N-methyl anilines via formimidate intermediates
Author/Authors
Nan Sun، نويسنده , , Shuai Wang، نويسنده , , Weimin Mo، نويسنده , , Baoxiang Hu، نويسنده , , Zhenlu Shen، نويسنده , , Xinquan Hu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
7
From page
7142
To page
7148
Abstract
A general procedure for the preparation of mono-N-methyl anilines has been developed with excellent yields. This protocol relies on a NaBH3(OAc) reduction of formimidate intermediates that are quantitatively generated by treatment of primary substituted anilines with triethyl orthoformate under the catalysis of MCM-41-SO3H mesoporous zeolite. The newly developed procedure was facile, efficient, and environmentally benign.
Keywords
Mono-N-methyl anilines , Formimidate , MCM-41-SO3H mesoporous zeolite , NaBH3(OAc) reduction
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1101244
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