Title of article
Morita–Baylis–Hillman reaction of indole-2-carboxaldehyde: new vistas for indole-annulated systems
Author/Authors
Gopal Patra and Subhasish Biswas، نويسنده , , Virender Singh، نويسنده , , Sanjay Batra، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
6
From page
7781
To page
7786
Abstract
DABCO-mediated Morita–Baylis–Hillman reactions of several 1-substituted-indole-2-carboxaldehydes are disclosed. It was discovered that carboethoxy or tert-butoxycarbonyl groups installed at N-1 undergo cleavage under the reaction conditions to afford 2-substituted indoles. Utility of the N-substituted adducts for preparing a variety of annulated indoles has been exemplified.
Keywords
Morita–Baylis–Hillman , Indole-2-carboxaldehyde , RCM , Heck-reaction , Reductive cyclization
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1101318
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