Title of article :
Highly (beta)-Selective Mannosylation towards Manpl-4GlcNAc Synthesis: TMSB(C6F5)4 as a Lewis Acid/Cation Trap Catalyst
Author/Authors :
Tanaka، Shin-ichi نويسنده , , Fukase، Koichi نويسنده , , Takashina، Mamoru نويسنده , , Tokimoto، Hiroomi نويسنده , , Fujimoto، Yukari نويسنده , , Tanaka، Katsunori نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
Highly (beta)-selective mannosylation of 4,6-O-benzylidenemannopyranosyl-N-phenyltrifluoroacetimidate ((alpha)/(beta), 5:95, 93% yield) has been realized by utilizing a dual Lewis acid/cation trap catalyst, TMSB(C6F5)4. The obtained Man(beta)l-4GlcNTroc unit can be readily converted to a variety of N-linked oligosaccharides.
Keywords :
Lewis acid , TMSB(C6F5)4 Man(beta)l-4GlcNAc synthesis , (beta)-glycoside , stereoselective mannosylation , oligosaccharides
