Title of article :
Ammonia in Ugi Reactions - Four-Component versus Six-Component Couplings
Author/Authors :
Hebach، Christina نويسنده , , Kazmaier، Uli نويسنده , , Pick، Rigobert نويسنده , , Bauer، Michael نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
If ammonia is used as amine component in Ugi reactions, the desired peptide sometimes is obtained only as the minor product or in traces. Side reactions such as six-component couplings are responsible for this observation. These side reactions can be suppressed or favoured depending on the reaction conditions used.
Keywords :
Ammonia , peptide , Ugi reactions , six-component coupling
